Version 5.4
Bos taurus Protein: ANGPTL4
Summary
InnateDB Protein IDBP-693808.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANGPTL4
Protein Name angiopoietin-4 precursor
Synonyms ANGPTL4;
Species Bos taurus
Ensembl Protein ENSBTAP00000029073
InnateDB Gene IDBG-641435 (ANGPTL4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0030297 transmembrane receptor protein tyrosine kinase activator activity
GO:0030971 receptor tyrosine kinase binding
Biological Process
GO:0001525 angiogenesis
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity
GO:0010595 positive regulation of endothelial cell migration
GO:0016525 negative regulation of angiogenesis
GO:0043066 negative regulation of apoptotic process
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0045766 positive regulation of angiogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
PFAM PF00147
PRINTS
PIRSF
SMART SM00186
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B2Z4B2
UniProt Splice Variant
Entrez Gene 617915
UniGene Bt.29197
RefSeq NP_001069951
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036371 DAAA02036372 EU599227 EU599233
GenPept ACD50903 ACD50909

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca