InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: C20ORF18

Summary

InnateDB Protein

IDBP-693835.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

C20ORF18

Protein Name

ranBP-type and C3HC4-type zinc finger-containing protein 1

Synonyms

C20ORF18;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022612

InnateDB Gene

IDBG-641465 (C20ORF18)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 61 interaction(s) predicted by orthology.

Predicted by orthology
Total	61 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043130	ubiquitin binding
GO:0046872	metal ion binding

Biological Process

GO:0000209	protein polyubiquitination
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0043065	positive regulation of apoptotic process
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0050852	T cell receptor signaling pathway
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0060546	negative regulation of necroptotic process
GO:0097039	protein linear polyubiquitination
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0071797

LUBAC complex

Protein Structure and Domains

PDB ID

InterPro

IPR000626 Ubiquitin-like
IPR001841 Zinc finger, RING-type
IPR001876 Zinc finger, RanBP2-type
IPR002867 Zinc finger, C6HC-type
IPR018957 Zinc finger, C3HC4 RING-type
IPR029071 Ubiquitin-related domain

PFAM