Bos taurus Protein: STRADA
Summary
InnateDB Protein IDBP-694023.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STRADA
Protein Name STE20-related kinase adapter protein alpha
Synonyms LYK5;
Species Bos taurus
Ensembl Protein ENSBTAP00000000061
InnateDB Gene IDBG-641634 (STRADA)
Protein Structure
UniProt Annotation
Function Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250UniProtKB:Q7RTN6}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0030295 protein kinase activator activity
Biological Process
GO:0006468 protein phosphorylation
GO:0006611 protein export from nucleus
GO:0007049 cell cycle
GO:0032147 activation of protein kinase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF07714
PRINTS PR00109
PIRSF
SMART SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5E9J9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 515024
UniGene Bt.20073
RefSeq NP_001015603
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT020921
GenPept AAX08938