InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DGKH

Summary

InnateDB Protein

IDBP-694319.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DGKH

Protein Name

diacylglycerol kinase, eta

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000027473

InnateDB Gene

IDBG-641892 (DGKH)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003951	NAD+ kinase activity
GO:0004143	diacylglycerol kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008152	metabolic process
GO:0010033	response to organic substance
GO:0016310	phosphorylation
GO:0035556	intracellular signal transduction
GO:0051260	protein homooligomerization

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016023	cytoplasmic membrane-bounded vesicle

Protein Structure and Domains

PDB ID

InterPro

IPR000756 Diacylglycerol kinase, accessory domain
IPR001206 Diacylglycerol kinase, catalytic domain
IPR001660 Sterile alpha motif domain
IPR001849 Pleckstrin homology domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain
IPR021129 Sterile alpha motif, type 1

PFAM

PF00609
PF00781
PF00169
PF00130
PF07647
PF00536

PRINTS

PIRSF

SMART

SM00045
SM00046
SM00454
SM00233
SM00109

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite