InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: DGKH

Summary

InnateDB Gene

IDBG-641892.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DGKH

Gene Name

diacylglycerol kinase delta

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000020616

Encoded Proteins

IDBP-694319

diacylglycerol kinase, eta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000077044:
This gene encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid. Diacylglycerol and phosphatidic acid are two lipids that act as second messengers in signaling cascades. Their cellular concentrations are regulated by the encoded protein, and so it is thought to play an important role in cellular signal transduction. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:113703381-113783354

Strand

Forward strand

Band

Transcripts

ENSBTAT00000027473

ENSBTAP00000027473

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003951	NAD+ kinase activity
GO:0004143	diacylglycerol kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008152	metabolic process
GO:0010033	response to organic substance
GO:0016310	phosphorylation
GO:0035556	intracellular signal transduction
GO:0051260	protein homooligomerization