Version 5.4
Bos taurus Protein: PDE6G
Summary
InnateDB Protein IDBP-694964.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDE6G
Protein Name Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000459
InnateDB Gene IDBG-642510 (PDE6G)
Protein Structure
UniProt Annotation
Function Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0030553 cGMP binding
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
Biological Process
GO:0000187 activation of MAPK activity
GO:0007601 visual perception
GO:0008152 metabolic process
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway
GO:0050896 response to stimulus
Cellular Component
GO:0097381 photoreceptor disc membrane
Protein Structure and Domains
PDB ID
InterPro IPR006952 Retinal cGMP phosphodiesterase, gamma subunit
PFAM PF04868
PRINTS
PIRSF PIRSF000969
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P04972
PhosphoSite PhosphoSite-P04972
TrEMBL
UniProt Splice Variant
Entrez Gene 281977
UniGene Bt.54
RefSeq NP_776846
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL X04270 X04823
GenPept CAA27821 CAA28507

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca