InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: TRIM28

Summary

InnateDB Protein

IDBP-695030.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRIM28

Protein Name

tripartite motif containing 28

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000008424

InnateDB Gene

IDBG-642502 (TRIM28)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 152 interaction(s) predicted by orthology.

Predicted by orthology
Total	152 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003713	transcription coactivator activity
GO:0003714	transcription corepressor activity
GO:0004672	protein kinase activity
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0031625	ubiquitin protein ligase binding
GO:0035851	Krueppel-associated box domain binding
GO:0043565	sequence-specific DNA binding
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding
GO:0070087	chromo shadow domain binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001837	epithelial to mesenchymal transition
GO:0006281	DNA repair
GO:0006468	protein phosphorylation
GO:0016567	protein ubiquitination
GO:0042993	positive regulation of transcription factor import into nucleus
GO:0045087	innate immune response
GO:0045739	positive regulation of DNA repair
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0046777	protein autophosphorylation
GO:0051259	protein oligomerization
GO:0060028	convergent extension involved in axis elongation
GO:0060669	embryonic placenta morphogenesis
GO:1902187	negative regulation of viral release from host cell

Cellular Component

GO:0000785	chromatin
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005719	nuclear euchromatin
GO:0005720	nuclear heterochromatin

Protein Structure and Domains

PDB ID

InterPro

IPR000315 Zinc finger, B-box
IPR001487 Bromodomain
IPR001965 Zinc finger, PHD-type
IPR003649 B-box, C-terminal
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger

PFAM

PF00643
PF00439
PF00628

PRINTS

PR00503

PIRSF

SMART

SM00336
SM00297
SM00249
SM00502

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt