InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: D2HGDH

Summary

InnateDB Protein

IDBP-695174.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

D2HGDH

Protein Name

D-2-hydroxyglutarate dehydrogenase, mitochondrial

Synonyms

D2HGD;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003690

InnateDB Gene

IDBG-642692 (D2HGDH)

Protein Structure

UniProt Annotation

Function

Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity
GO:0016491	oxidoreductase activity
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
GO:0050660	flavin adenine dinucleotide binding

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005739

mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR004113 FAD-linked oxidase, C-terminal
IPR006094 FAD linked oxidase, N-terminal
IPR016164 FAD-linked oxidase-like, C-terminal
IPR016166 FAD-binding, type 2

PFAM

PF02913
PF01565

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q1JPD3

PhosphoSite