InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ARSA

Summary

InnateDB Protein

IDBP-695316.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ARSA

Protein Name

Arylsulfatase A

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021364

InnateDB Gene

IDBG-642822 (ARSA)

Protein Structure

UniProt Annotation

Function

Hydrolyzes cerebroside sulfate. {ECO:0000250}.

Subcellular Localization

Lysosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004098	cerebroside-sulfatase activity
GO:0005509	calcium ion binding
GO:0008484	sulfuric ester hydrolase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0007339	binding of sperm to zona pellucida
GO:0008152	metabolic process

Cellular Component

GO:0005764	lysosome
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000917 Sulfatase
IPR017850 Alkaline-phosphatase-like, core domain

PFAM

PF00884

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q08DD1

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

505514

UniGene

Bt.1076

RefSeq

NP_001068673

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC123816

GenPept

AAI23817