Version 5.4
Bos taurus Protein: ACOX1
Summary
InnateDB Protein IDBP-695657.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACOX1
Protein Name peroxisomal acyl-coenzyme A oxidase 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029362
InnateDB Gene IDBG-643126 (ACOX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003995 acyl-CoA dehydrogenase activity
GO:0003997 acyl-CoA oxidase activity
GO:0005102 receptor binding
GO:0016401 palmitoyl-CoA oxidase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0030165 PDZ domain binding
GO:0047485 protein N-terminus binding
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0006629 lipid metabolic process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0006693 prostaglandin metabolic process
GO:0007283 spermatogenesis
GO:0008152 metabolic process
GO:0016559 peroxisome fission
GO:0019395 fatty acid oxidation
GO:0055088 lipid homeostasis
GO:0055114 oxidation-reduction process
GO:2000189 positive regulation of cholesterol homeostasis
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002655 Acyl-CoA oxidase, C-terminal
IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain
IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal
IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain
IPR012258 Acyl-CoA oxidase
PFAM PF01756
PF02770
PF00441
PRINTS
PIRSF PIRSF000168
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MBU5
UniProt Splice Variant
Entrez Gene 513996
UniGene
RefSeq NP_001030366
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049507 DAAA02049508 DAAA02049509
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca