InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: S1PR2

Summary

InnateDB Protein

IDBP-695786.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

S1PR2

Protein Name

sphingosine 1-phosphate receptor 2

Synonyms

EDG5;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003550

InnateDB Gene

IDBG-643243 (S1PR2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0005178	integrin binding
GO:0038036	sphingosine-1-phosphate receptor activity

Biological Process

GO:0003376	sphingosine-1-phosphate signaling pathway
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0090394	negative regulation of excitatory postsynaptic membrane potential
GO:1903142	positive regulation of establishment of endothelial barrier

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001671 Melanocortin/ACTH receptor
IPR004061 Sphingosine 1-phosphate receptor
IPR004063 EDG-5 sphingosine 1-phosphate receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00534
PR01523
PR01525

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite