InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: WDFY3

Summary

InnateDB Protein

IDBP-695817.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

WDFY3

Protein Name

WD repeat and FYVE domain containing 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000053365

InnateDB Gene

IDBG-643259 (WDFY3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
GO:0005488	binding
GO:0005515	protein binding
GO:0005545	1-phosphatidylinositol binding
GO:0046872	metal ion binding

Biological Process

GO:0016239	positive regulation of macroautophagy
GO:0035973	aggrephagy

Cellular Component

GO:0005635	nuclear envelope
GO:0005737	cytoplasm
GO:0005776	autophagic vacuole
GO:0016234	inclusion body
GO:0016605	PML body
GO:0019898	extrinsic component of membrane
GO:0034274	Atg12-Atg5-Atg16 complex

Protein Structure and Domains

PDB ID

InterPro

IPR000306 FYVE zinc finger
IPR000409 BEACH domain
IPR001680 WD40 repeat
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR011011 Zinc finger, FYVE/PHD-type
IPR013763 Cyclin-like
IPR016024 Armadillo-type fold
IPR017455 Zinc finger, FYVE-related
IPR017986 WD40-repeat-containing domain

PFAM

PF01363
PF02138
PF00400

PRINTS

PIRSF

SMART

SM00064
SM01026
SM00320
SM00385

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite