Bos taurus Protein: DES
Summary
InnateDB Protein IDBP-696616.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DES
Protein Name Desmin
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007041
InnateDB Gene IDBG-644007 (DES)
Protein Structure
UniProt Annotation
Function Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
GO:0042802 identical protein binding
Biological Process
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005882 intermediate filament
GO:0005916 fascia adherens
GO:0030018 Z disc
GO:0031594 neuromuscular junction
GO:0042383 sarcolemma
GO:0043292 contractile fiber
Protein Structure and Domains
PDB ID
InterPro IPR001664 Intermediate filament protein
IPR006821 Intermediate filament head, DNA-binding domain
IPR009053 Prefoldin
PFAM PF00038
PF04732
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O62654
PhosphoSite PhosphoSite-
TrEMBL Q862F7
UniProt Splice Variant
Entrez Gene 280765
UniGene Bt.6141
RefSeq NP_001075044
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB011673 AB011675 AB099038 BC133410
GenPept AAI33411 BAA25133 BAA25135 BAC56528