InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: KAT5

Summary

InnateDB Protein

IDBP-696848.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KAT5

Protein Name

K(lysine) acetyltransferase 5

Synonyms

HTATIP;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007328

InnateDB Gene

IDBG-644226 (KAT5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 176 interaction(s) predicted by orthology.

Predicted by orthology
Total	176 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
GO:0070491	repressing transcription factor binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006302	double-strand break repair
GO:0006355	regulation of transcription, DNA-templated
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0010212	response to ionizing radiation
GO:0016573	histone acetylation
GO:0032703	negative regulation of interleukin-2 production
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0071392	cellular response to estradiol stimulus

Cellular Component

GO:0000812	Swr1 complex
GO:0005634	nucleus
GO:0005667	transcription factor complex
GO:0005730	nucleolus
GO:0032777	Piccolo NuA4 histone acetyltransferase complex
GO:0035267	NuA4 histone acetyltransferase complex

Protein Structure and Domains

PDB ID

InterPro

IPR000953 Chromo domain/shadow
IPR002717 MOZ/SAS-like protein
IPR016181 Acyl-CoA N-acyltransferase
IPR016197 Chromo domain-like
IPR025995 RNA binding activity-knot of a chromodomain

PFAM

PF01853
PF11717

PRINTS

PIRSF

SMART

SM00298

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite