InnateDB Protein
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IDBP-697369.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ARPC4
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Protein Name
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Actin-related protein 2/3 complex subunit 4
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000010469
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InnateDB Gene
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IDBG-644712 (ARPC4)
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Protein Structure
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Function |
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytoskeleton {ECO:0000250}. Cell projection {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
22 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008384
ARP2/3 complex, 20kDa subunit (P20-Arc)
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PFAM |
PF05856
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q148J6
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
539459
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UniGene |
Bt.106660
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RefSeq |
NP_001069631
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC118263
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GenPept |
AAI18264
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