Version 5.4
Bos taurus Protein: SLC9A1
Summary
InnateDB Protein IDBP-697763.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC9A1
Protein Name sodium/hydrogen exchanger 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000048292
InnateDB Gene IDBG-645084 (SLC9A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015297 antiporter activity
GO:0015299 solute:proton antiporter activity
GO:0015385 sodium:proton antiporter activity
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0001101 response to acid
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0006814 sodium ion transport
GO:0006885 regulation of pH
GO:0010447 response to acidity
GO:0035725 sodium ion transmembrane transport
GO:0051453 regulation of intracellular pH
GO:0055007 cardiac muscle cell differentiation
GO:0055085 transmembrane transport
GO:1902600 hydrogen ion transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001970 Na+/H+ exchanger, isoform 1 (NHE1)
IPR004709 Na+/H+ exchanger
IPR006153 Cation/H+ exchanger
PFAM PF00999
PRINTS PR01085
PR01084
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MHK2
UniProt Splice Variant
Entrez Gene 317654
UniGene Bt.528
RefSeq NP_777258
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02006358
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca