InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MBD3

Summary

InnateDB Protein

IDBP-698394.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MBD3

Protein Name

methyl-CpG-binding domain protein 3

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000003926

InnateDB Gene

IDBG-645666 (MBD3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 61 interaction(s) predicted by orthology.

Predicted by orthology
Total	61 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0008327	methyl-CpG binding
GO:0031492	nucleosomal DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001701	in utero embryonic development
GO:0006346	methylation-dependent chromatin silencing
GO:0009888	tissue development
GO:0016573	histone acetylation
GO:0043044	ATP-dependent chromatin remodeling

Cellular Component

GO:0000785	chromatin
GO:0000790	nuclear chromatin
GO:0000792	heterochromatin
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016581	NuRD complex
GO:0043234	protein complex