Version 5.4
Bos taurus Protein: BT.18085
Summary
InnateDB Protein IDBP-698981.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.18085
Protein Name sterol regulatory element-binding protein cleavage-activating protein
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000020961
InnateDB Gene IDBG-646200 (BT.18085)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008158 hedgehog receptor activity
Biological Process
GO:0001666 response to hypoxia
GO:0008203 cholesterol metabolic process
GO:0019217 regulation of fatty acid metabolic process
GO:0032868 response to insulin
GO:0032933 SREBP signaling pathway
GO:0042304 regulation of fatty acid biosynthetic process
GO:0045540 regulation of cholesterol biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000731 Sterol-sensing domain
IPR001680 WD40 repeat
IPR003392 Patched
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PF02460
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MQ33
UniProt Splice Variant
Entrez Gene 507878
UniGene Bt.18085
RefSeq NP_001095359
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054449
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca