InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: CAMK2A

Summary

InnateDB Protein

IDBP-699066.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CAMK2A

Protein Name

calcium/calmodulin-dependent protein kinase type II subunit alpha

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000026762

InnateDB Gene

IDBG-646280 (CAMK2A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 42 interaction(s) predicted by orthology.

Predicted by orthology
Total	42 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004683	calmodulin-dependent protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0035254	glutamate receptor binding

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0006468	protein phosphorylation
GO:0006816	calcium ion transport
GO:0016310	phosphorylation
GO:0046777	protein autophosphorylation
GO:0046928	regulation of neurotransmitter secretion
GO:0048168	regulation of neuronal synaptic plasticity
GO:0051092	positive regulation of NF-kappaB transcription factor activity

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF08332

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q08E45

UniProt Splice Variant

Entrez Gene

530719

UniGene

Bt.61581

RefSeq

NP_001069406

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC123428 DAAA02020627

GenPept

AAI23429