Version 5.4
Bos taurus Protein: MCM2
Summary
InnateDB Protein IDBP-699340.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MCM2
Protein Name minichromosome maintenance complex component 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000019121
InnateDB Gene IDBG-646521 (MCM2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 76 interaction(s) predicted by orthology.
Predicted by orthology
Total 76 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016851 magnesium chelatase activity
GO:0016887 ATPase activity
GO:0042393 histone binding
Biological Process
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006270 DNA replication initiation
GO:0006334 nucleosome assembly
GO:0015979 photosynthesis
GO:0015995 chlorophyll biosynthetic process
GO:0071353 cellular response to interleukin-4
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005664 nuclear origin of replication recognition complex
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
GO:0042555 MCM complex
Protein Structure and Domains
PDB ID
InterPro IPR000523 Magnesium chelatase, ChlI subunit
IPR001208 Mini-chromosome maintenance, DNA-dependent ATPase
IPR008045 DNA replication licensing factor Mcm2
IPR011703 ATPase, AAA-3
IPR011704 ATPase, dynein-related, AAA domain
IPR012340 Nucleic acid-binding, OB-fold
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF01078
PF00493
PF12619
PF07726
PF07728
PRINTS PR01657
PR01658
PIRSF
SMART SM00350
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1N506
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:6944
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054693 DAAA02054694
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca