InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PAM

Summary

InnateDB Protein

IDBP-699431.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAM

Protein Name

peptidyl-glycine alpha-amidating monooxygenase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000016466

InnateDB Gene

IDBG-646608 (PAM)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004497	monooxygenase activity
GO:0004504	peptidylglycine monooxygenase activity
GO:0004598	peptidylamidoglycolate lyase activity
GO:0005507	copper ion binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

Biological Process

GO:0001519	peptide amidation
GO:0006518	peptide metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000323 Copper type II, ascorbate-dependent monooxygenase, N-terminal
IPR000720 Peptidyl-glycine alpha-amidating monooxygenase
IPR001258 NHL repeat
IPR008977 PHM/PNGase F domain
IPR013017 NHL repeat, subgroup

PFAM

PF01082
PF01436

PRINTS

PR00790

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite