InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SLC12A1

Summary

InnateDB Protein

IDBP-699509.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC12A1

Protein Name

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

Synonyms

BSC1;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000043868

InnateDB Gene

IDBG-646682 (SLC12A1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005515	protein binding
GO:0015377	cation:chloride symporter activity

Biological Process

GO:0001822	kidney development
GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0007588	excretion
GO:0048878	chemical homeostasis
GO:0055085	transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001991 Sodium:dicarboxylate symporter
IPR002443 Na/K/Cl co-transporter
IPR002445 Na/K/Cl co-transporter 2
IPR004841 Amino acid permease/ SLC12A domain
IPR004842 Na/K/Cl co-transporter superfamily
IPR013612 Amino acid permease, N-terminal

PFAM

PF00375
PF00324
PF08403

PRINTS

PR00173
PR01207
PR01209

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite