Bos taurus Protein: FZD5
Summary
InnateDB Protein IDBP-700562.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FZD5
Protein Name frizzled family receptor 5
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000041785
InnateDB Gene IDBG-647764 (FZD5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
GO:0019901 protein kinase binding
GO:0031625 ubiquitin protein ligase binding
GO:0042813 Wnt-activated receptor activity
Biological Process
GO:0000578 embryonic axis specification
GO:0001525 angiogenesis
GO:0001944 vasculature development
GO:0007166 cell surface receptor signaling pathway
GO:0007275 multicellular organismal development
GO:0008285 negative regulation of cell proliferation
GO:0008595 anterior/posterior axis specification, embryo
GO:0016055 Wnt signaling pathway
GO:0031076 embryonic camera-type eye development
GO:0031077 post-embryonic camera-type eye development
GO:0032729 positive regulation of interferon-gamma production
GO:0033077 T cell differentiation in thymus
GO:0043507 positive regulation of JUN kinase activity
GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048469 cell maturation
GO:0060061 Spemann organizer formation
GO:0060070 canonical Wnt signaling pathway
GO:0060561 apoptotic process involved in morphogenesis
GO:0060670 branching involved in labyrinthine layer morphogenesis
GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development
GO:0060716 labyrinthine layer blood vessel development
GO:0060718 chorionic trophoblast cell differentiation
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0071219 cellular response to molecule of bacterial origin
GO:1901382 regulation of chorionic trophoblast cell proliferation
GO:2000810 regulation of tight junction assembly
Cellular Component
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005923 tight junction
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000539 Frizzled protein
IPR017981 GPCR, family 2-like
IPR020067 Frizzled domain
PFAM PF01534
PF01392
PRINTS PR00489
PIRSF
SMART SM00063
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MGM1
UniProt Splice Variant
Entrez Gene 538536
UniGene Bt.87182
RefSeq XP_005197567
HUGO HGNC:4043
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02005711
GenPept