Version 5.4
Homo sapiens Protein: BIRC5
Summary
InnateDB Protein IDBP-70556.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BIRC5
Protein Name baculoviral IAP repeat containing 5
Synonyms API4; EPR-1;
Species Homo sapiens
Ensembl Protein ENSP00000301633
InnateDB Gene IDBG-70554 (BIRC5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 74 experimentally validated interaction(s) in this database.
Experimentally validated
Total 74 [view]
Protein-Protein 64 [view]
Protein-DNA 9 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0007346 regulation of mitotic cell cycle
GO:0043524 negative regulation of neuron apoptotic process
GO:0045087 innate immune response (InnateDB)
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061469 regulation of type B pancreatic cell proliferation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001370 Baculoviral inhibition of apoptosis protein repeat
PFAM PF00653
PRINTS
PIRSF
SMART SM00238
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H3BLT4
UniProt Splice Variant
Entrez Gene 332
UniGene Hs.742107
RefSeq NP_001012271
HUGO HGNC:593
OMIM 603352
CCDS CCDS32752
HPRD 04520
IMGT
EMBL AC087645
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca