Version 5.4
Homo sapiens Protein: KIAA0391
Summary
InnateDB Protein IDBP-706811.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KIAA0391
Protein Name
Synonyms IOTA; MRPP3; p27K; PRORP; PROS27;
Species Homo sapiens
Ensembl Protein ENSP00000454657
InnateDB Gene IDBG-545199 (KIAA0391)
Protein Structure
UniProt Annotation
Function Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. {ECO:0000269PubMed:18984158}.
Subcellular Localization Mitochondrion {ECO:0000269PubMed:18984158}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008033 tRNA processing
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-O15091
TrEMBL S4R416
UniProt Splice Variant
Entrez Gene 9692
UniGene Hs.707099
RefSeq XP_005268294
HUGO HGNC:19958
OMIM 609947
CCDS CCDS32063
HPRD
IMGT
EMBL AB002389 AK301931 AK303508 AK304066 AL121594 BC032221 BC044580 BX161394 BX161487 CH471078
GenPept AAH32221 AAH44580 BAA20845 BAG63351 BAG64540 BAG64973 CAD61881 CAD61937 EAW65878 EAW65879 EAW65880 EAW65881 EAW65882 EAW65883 EAW65884

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca