InnateDB Protein
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IDBP-707509.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cldn14
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Protein Name
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Synonyms
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AI851731;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000136156
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InnateDB Gene
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IDBG-178368 (Cldn14)
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Protein Structure
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Function |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
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Subcellular Localization |
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Expressed in all sensory epithelia of the inner ear vestibular organs, as well as in liver and kidney. {ECO:0000269PubMed:11163249}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1860425
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InterPro |
IPR003556
Claudin-14
IPR004031
PMP-22/EMP/MP20/Claudin superfamily
IPR006187
Claudin
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PFAM |
PF00822
PF13903
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PRINTS |
PR01077
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9Z0S3
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PhosphoSite |
PhosphoSite-Q9Z0S3
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TrEMBL |
A2RSP0
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UniProt Splice Variant |
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Entrez Gene |
56173
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UniGene |
Mm.328716
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RefSeq |
NP_001159397
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MGI ID |
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MGI Symbol |
Cldn14
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OMIM |
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CCDS |
CCDS28345
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HPRD |
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IMGT |
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EMBL |
AF124429
AF314089
AK020255
BC132183
BC138497
CH466602
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GenPept |
AAD17323
AAG60051
AAI32184
AAI38498
BAB32041
EDL03752
EDL03753
EDL03754
EDL03755
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