Version 5.4
Mus musculus Protein: Scnn1a
Summary
InnateDB Protein IDBP-715087.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Scnn1a
Protein Name
Synonyms ENaC; mENaC; SCNEA; Scnn1;
Species Mus musculus
Ensembl Protein ENSMUSP00000134940
InnateDB Gene IDBG-189817 (Scnn1a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005272 sodium channel activity
GO:0015280 ligand-gated sodium channel activity
GO:0050699 WW domain binding
Biological Process
GO:0006814 sodium ion transport
GO:0035725 sodium ion transmembrane transport
GO:0050878 regulation of body fluid levels
Cellular Component
GO:0005829 cytosol
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030864 cortical actin cytoskeleton
GO:0034706 sodium channel complex
Protein Structure and Domains
PDB ID MGI:101782
InterPro IPR001873 Na+ channel, amiloride-sensitive
IPR004724 Epithelial sodium channel
PFAM PF00858
PRINTS PR01078
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q80YC1
UniProt Splice Variant
Entrez Gene 20276
UniGene Mm.144114
RefSeq
MGI ID
MGI Symbol Scnn1a
OMIM
CCDS
HPRD
IMGT
EMBL AC140324 BC049952
GenPept AAH49952

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca