Version 5.4
Mus musculus Protein: Lhx8
Summary
InnateDB Protein IDBP-716876.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lhx8
Protein Name
Synonyms L3; Lhx7;
Species Mus musculus
Ensembl Protein ENSMUSP00000136047
InnateDB Gene IDBG-706462 (Lhx8)
Protein Structure
UniProt Annotation
Function Transcription factor involved in differentiation of certain neurons and mesenchymal cells.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007611 learning or memory
GO:0008585 female gonad development
GO:0021879 forebrain neuron differentiation
GO:0021884 forebrain neuron development
GO:0042475 odontogenesis of dentin-containing tooth
Cellular Component
GO:0001674 female germ cell nucleus
Protein Structure and Domains
PDB ID MGI:1096343
InterPro IPR001356 Homeobox domain
IPR001781 Zinc finger, LIM-type
IPR009057 Homeodomain-like
PFAM PF00046
PF00412
PRINTS
PIRSF
SMART SM00389
SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35652
PhosphoSite PhosphoSite-
TrEMBL V9GX93
UniProt Splice Variant
Entrez Gene 16875
UniGene Mm.422369
RefSeq NP_034843
MGI ID
MGI Symbol Lhx8
OMIM
CCDS CCDS17926
HPRD
IMGT
EMBL AB007596 AC119163 AJ000338 AK165733 BC125281 BC125283 BC144768 CH466532 D49658
GenPept AAI25282 AAI25284 AAI44769 BAA21649 BAA28628 BAE38359 CAA04012 EDL11894

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca