InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Eif5a

Summary

InnateDB Protein

IDBP-718867.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Eif5a

Protein Name

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000137459

InnateDB Gene

IDBG-264162 (Eif5a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003746	translation elongation factor activity
GO:0043022	ribosome binding

Biological Process

GO:0006452	translational frameshifting
GO:0007568	aging
GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
GO:0043065	positive regulation of apoptotic process
GO:0043066	negative regulation of apoptotic process
GO:0045901	positive regulation of translational elongation
GO:0045905	positive regulation of translational termination
GO:0051149	positive regulation of muscle cell differentiation

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

MGI:106248

InterPro

IPR012340 Nucleic acid-binding, OB-fold
IPR020189 Translation elongation factor, IF5A C-terminal

PFAM

PF01287

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

J3QPS8

UniProt Splice Variant

Entrez Gene

276770

UniGene

RefSeq

MGI ID

MGI Symbol

Eif5a

OMIM

CCDS

HPRD

IMGT

EMBL

AL596185

GenPept