Version 5.4
Homo sapiens Protein: DFFA
Summary
InnateDB Protein IDBP-722534.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DFFA
Protein Name
Synonyms DFF-45; DFF1; ICAD;
Species Homo sapiens
Ensembl Protein ENSP00000468395
InnateDB Gene IDBG-89047 (DFFA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 47 [view]
Protein-Protein 46 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 1 [view]
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0007165 signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000488 Death domain
IPR003508 CIDE-N domain
IPR015121 DNA fragmentation factor 45kDa, middle domain
PFAM PF00531
PF02017
PF09033
PRINTS
PIRSF
SMART SM00005
SM00266
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL K7ERT1
UniProt Splice Variant
Entrez Gene 1676
UniGene Hs.603104
RefSeq
HUGO HGNC:2772
OMIM 601882
CCDS
HPRD 03531
IMGT
EMBL AL354956
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca