InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PIAS2

Summary

InnateDB Protein

IDBP-725589.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PIAS2

Protein Name

Synonyms

ARIP3; DIP; MIZ; MIZ1; PIASX; PIASX-ALPHA; PIASX-BETA; SIZ2; ZMIZ4;

Species

Homo sapiens

Ensembl Protein

ENSP00000465676

InnateDB Gene

IDBG-3013 (PIAS2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 96 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	97 [view]
Protein-Protein	95 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019789	SUMO ligase activity
GO:0031625	ubiquitin protein ligase binding
GO:0050681	androgen receptor binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0008152	metabolic process
GO:0016925	protein sumoylation
GO:0030521	androgen receptor signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0045667	regulation of osteoblast differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060766	negative regulation of androgen receptor signaling pathway