Version 5.4
Homo sapiens Protein: MYL9
Summary
InnateDB Protein IDBP-72765.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYL9
Protein Name myosin, light chain 9, regulatory
Synonyms LC20; MLC-2C; MLC2; MRLC1; MYRL2;
Species Homo sapiens
Ensembl Protein ENSP00000217313
InnateDB Gene IDBG-72761 (MYL9)
Protein Structure
UniProt Annotation
Function Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
Subcellular Localization
Disease Associations
Tissue Specificity Smooth muscle tissues and in some, but not all, nonmuscle cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008307 structural constituent of muscle
Biological Process
GO:0006936 muscle contraction
GO:0006937 regulation of muscle contraction
GO:0007411 axon guidance
Cellular Component
GO:0005829 cytosol
GO:0005859 muscle myosin complex
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P24844
PhosphoSite PhosphoSite-P24844
TrEMBL
UniProt Splice Variant
Entrez Gene 10398
UniGene
RefSeq NP_852667
HUGO HGNC:15754
OMIM 609905
CCDS CCDS13277
HPRD 17619
IMGT
EMBL AF176043 AL050318 BC002648 CH471077 D82057 J02854
GenPept AAA59852 AAH02648 AAQ13654 BAB88917 CAB75369 CAC34440 EAW76129 EAW76131 EAW76132 EAW76133 EAW76134

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca