InnateDB Protein
|
IDBP-73672.7
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
UBE4A
|
Protein Name
|
ubiquitination factor E4A
|
Synonyms
|
E4; UBOX2; UFD2;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000252108
|
InnateDB Gene
|
IDBG-73670 (UBE4A)
|
Protein Structure
|
|
Function |
Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3. {ECO:0000250}.
|
Subcellular Localization |
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
17
[view]
|
Protein-Protein |
17
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR003613
U box domain
IPR019474
Ubiquitin conjugation factor E4, core
|
PFAM |
PF04564
PF10408
|
PRINTS |
|
PIRSF |
|
SMART |
SM00504
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q14139
|
PhosphoSite |
PhosphoSite-Q14139
|
TrEMBL |
B7Z7P0
|
UniProt Splice Variant |
|
Entrez Gene |
9354
|
UniGene |
Hs.75275
|
RefSeq |
NP_001191006
|
HUGO |
HGNC:12499
|
OMIM |
603753
|
CCDS |
CCDS55790
|
HPRD |
06793
|
IMGT |
|
EMBL |
AK302328
AP001267
AP001582
BC052643
BC062695
BC111417
BC112367
CH471065
D50916
EF445042
|
GenPept |
AAH52643
AAH62695
AAI11418
AAI12368
ACA06094
BAA09475
BAH13676
EAW67371
|
|
|