Version 5.4
Homo sapiens Protein: HMOX2
Summary
InnateDB Protein IDBP-750701.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HMOX2
Protein Name
Synonyms HO-2;
Species Homo sapiens
Ensembl Protein ENSP00000460926
InnateDB Gene IDBG-12855 (HMOX2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 56 experimentally validated interaction(s) in this database.
Experimentally validated
Total 56 [view]
Protein-Protein 55 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004392 heme oxygenase (decyclizing) activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001666 response to hypoxia
GO:0006778 porphyrin-containing compound metabolic process
GO:0006788 heme oxidation
GO:0006879 cellular iron ion homeostasis
GO:0042167 heme catabolic process
GO:0044281 small molecule metabolic process
GO:0055085 transmembrane transport
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002051 Haem oxygenase
IPR016053 Haem oxygenase-like
IPR016084 Haem oxygenase-like, multi-helical
PFAM PF01126
PRINTS PR00088
PIRSF PIRSF000343
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P30519
PhosphoSite PhosphoSite-P30519
TrEMBL
UniProt Splice Variant
Entrez Gene 3163
UniGene
RefSeq NP_001273200
HUGO HGNC:5014
OMIM 141251
CCDS CCDS66931
HPRD 00783
IMGT
EMBL AC007606 AF051306 AY771350 BC002396 BT019788 CH471112 D21243 S34389 W38932
GenPept AAB22110 AAC05297 AAH02396 AAV28730 AAV38591 BAA04789 EAW85299 EAW85300

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca