Version 5.4
Homo sapiens Protein: MKL2
Summary
InnateDB Protein IDBP-753360.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MKL2
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000459626
InnateDB Gene IDBG-15207 (MKL2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007517 muscle organ development
GO:0045844 positive regulation of striated muscle tissue development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003034 SAP domain
IPR004018 RPEL repeat
PFAM PF02037
PF02755
PRINTS
PIRSF
SMART SM00513
SM00707
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ULH7
PhosphoSite PhosphoSite-Q9ULH7
TrEMBL I3L0U1
UniProt Splice Variant
Entrez Gene 57496
UniGene Hs.715910
RefSeq XP_005255508
HUGO HGNC:29819
OMIM 609463
CCDS
HPRD 17577
IMGT
EMBL AB033069 AC012626 AC040173 AC130650 AK093577 AK127530 AK294765 AY374297 BC047761 BC136260 BC171750 CH471112 CR749797
GenPept AAH47761 AAI36261 AAI71750 AAQ82435 BAA86557 BAC04200 BAG54517 BAG57899 CAH18657 EAW85112

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca