Version 5.4
Homo sapiens Gene: MKL2
Summary
InnateDB Gene IDBG-15207.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MKL2
Gene Name MKL/myocardin-like 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186260
Encoded Proteins
IDBP-15209
MKL/myocardin-like 2
IDBP-751805
IDBP-744752
IDBP-749131
IDBP-752877
IDBP-753360
IDBP-752613
IDBP-746861
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:14071321-14266773
Strand Forward strand
Band p13.12
Transcripts
ENST00000318282 ENSP00000339086
ENST00000572588
ENST00000573051 ENSP00000460589
ENST00000572567 ENSP00000459879
ENST00000573434 ENSP00000460848
ENST00000575537
ENST00000575833
ENST00000574045 ENSP00000459205
ENST00000571589 ENSP00000459626
ENST00000575768
ENST00000572400
ENST00000574998 ENSP00000458340
ENST00000571770 ENSP00000459518
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0003007 heart morphogenesis
GO:0006351 transcription, DNA-templated
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0010467 gene expression
GO:0010468 regulation of gene expression
GO:0045844 positive regulation of striated muscle tissue development
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048514 blood vessel morphogenesis
GO:0048568 embryonic organ development
GO:0048738 cardiac muscle tissue development
GO:0051145 smooth muscle cell differentiation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000009569
View Gene Order
ENSBTAG00000008728
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.49143 Hs.624393 Hs.715910
RefSeq NM_014048 XM_005255451 XM_005255452 XM_005255453 XM_005255455 XM_005255457 XM_006720908 XM_006720909 XM_006720910 XM_006720911 XM_006720912 XM_006720914
HUGO
OMIM
CCDS CCDS32391
HPRD 17577
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca