Version 5.4
Homo sapiens Protein: ZNRD1
Summary
InnateDB Protein IDBP-75522.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNRD1
Protein Name zinc ribbon domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000365978
InnateDB Gene IDBG-75514 (ZNRD1)
Protein Structure
UniProt Annotation
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 14 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001054 RNA polymerase I activity
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006351 transcription, DNA-templated
GO:0006363 termination of RNA polymerase I transcription
Cellular Component
GO:0005736 DNA-directed RNA polymerase I complex
Protein Structure and Domains
PDB ID
InterPro IPR001222 Zinc finger, TFIIS-type
PFAM PF01096
PRINTS
PIRSF
SMART SM00440
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P1U0
PhosphoSite PhosphoSite-
TrEMBL Q2L6J2
UniProt Splice Variant
Entrez Gene 30834
UniGene
RefSeq NP_001265714
HUGO HGNC:13182
OMIM 607525
CCDS CCDS4670
HPRD 09601
IMGT
EMBL AB202082 AF024617 AF230337 AF230338 AL669914 AL671859 AL845439 BC010898 BC050608 BX088647 CH471081 CR457109
GenPept AAF40469 AAG50159 AAG50160 AAH10898 AAH50608 BAE78600 CAG33390 CAI17577 CAI18176 CAI18538 CAI95579 EAX03250 EAX03251 EAX03252

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca