Homo sapiens Gene: ZNRD1
Summary
InnateDB Gene IDBG-75514.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNRD1
Gene Name zinc ribbon domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000066379
Encoded Proteins
zinc ribbon domain containing 1
zinc ribbon domain containing 1
zinc ribbon domain containing 1
zinc ribbon domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30058899-30064909
Strand Forward strand
Band p22.1
Transcripts
ENST00000332435 ENSP00000331111
ENST00000359374 ENSP00000352333
ENST00000376785 ENSP00000365981
ENST00000376782 ENSP00000365978
ENST00000471008
ENST00000463141
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 14 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001054 RNA polymerase I activity
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006351 transcription, DNA-templated
GO:0006363 termination of RNA polymerase I transcription
Cellular Component
GO:0005736 DNA-directed RNA polymerase I complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
RNA Polymerase I Transcription pathway
RNA Polymerase I Promoter Escape pathway
Epigenetic regulation of gene expression pathway
RNA Polymerase I Promoter Clearance pathway
NoRC negatively regulates rRNA expression pathway
RNA Polymerase I Transcription Termination pathway
RNA Polymerase I Chain Elongation pathway
RNA Polymerase I Transcription Initiation pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Gene Expression pathway
Negative epigenetic regulation of rRNA expression pathway
KEGG
Purine metabolism pathway
Pyrimidine metabolism pathway
RNA polymerase pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001278785 NM_001278786 NM_014596 NM_170783
HUGO
OMIM
CCDS CCDS4670
HPRD 09601
IMGT
EMBL
GenPept
RNA Seq Atlas