InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TRIM15

Summary

InnateDB Protein

IDBP-75799.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRIM15

Protein Name

tripartite motif containing 15

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000365884

InnateDB Gene

IDBG-75795 (TRIM15)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	12 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0007500	mesodermal cell fate determination
GO:0032481	positive regulation of type I interferon production
GO:0045087	innate immune response (InnateDB)
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:1900246	positive regulation of RIG-I signaling pathway
GO:1901253	negative regulation of intracellular transport of viral material
GO:1902187	negative regulation of viral release from host cell

Cellular Component

GO:0005622

intracellular

Protein Structure and Domains

PDB ID

InterPro

IPR000315 Zinc finger, B-box
IPR001841 Zinc finger, RING-type
IPR001870 B30.2/SPRY domain
IPR003877 SPRY domain
IPR003879 Butyrophylin-like
IPR006574 SPRY-associated
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR018957 Zinc finger, C3HC4 RING-type

PFAM

PF00643
PF13639
PF14634
PF00622
PF13765
PF00097

PRINTS

PR01407

PIRSF

SMART

SM00336
SM00184
SM00449
SM00589

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt