Homo sapiens Protein: PRKCA
Summary
InnateDB Protein IDBP-758663.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRKCA
Protein Name
Synonyms AAG6; PKC-alpha; PKCA; PRKACA;
Species Homo sapiens
Ensembl Protein ENSP00000462087
InnateDB Gene IDBG-65194 (PRKCA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 148 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 148 [view]
Protein-Protein 148 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0035556 intracellular signal transduction
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR020454 Diacylglycerol/phorbol-ester binding
PFAM PF00168
PF00130
PRINTS PR00360
PR00008
PIRSF
SMART SM00239
SM00109
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q7Z727
UniProt Splice Variant
Entrez Gene 5578
UniGene Hs.708867
RefSeq XP_006722035
HUGO HGNC:9393
OMIM 176960
CCDS
HPRD 01498
IMGT
EMBL AC005918 AC005988 AC006263 AC006947 AC009452 AC060796 BC053321
GenPept AAH53321