Version 5.4
Homo sapiens Protein: GMFG
Summary
InnateDB Protein IDBP-759908.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GMFG
Protein Name
Synonyms GMF-GAMMA;
Species Homo sapiens
Ensembl Protein ENSP00000472249
InnateDB Gene IDBG-50169 (GMFG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0004860 protein kinase inhibitor activity
GO:0008047 enzyme activator activity
GO:0008083 growth factor activity
GO:0071933 Arp2/3 complex binding
Biological Process
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR002108 Actin-depolymerising factor homology domain
IPR011171 Glia maturation factor beta
PFAM PF00241
PRINTS
PIRSF PIRSF001788
SMART SM00102
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60234
PhosphoSite PhosphoSite-O60234
TrEMBL M0R1D2
UniProt Splice Variant
Entrez Gene 9535
UniGene Hs.619184
RefSeq NP_004868
HUGO HGNC:4374
OMIM 604104
CCDS CCDS12532
HPRD 06821
IMGT
EMBL AB001993 AC011445 AF038956 AF108022 AF108023 AF108024 AF108025 AF108026 AF108027 BC032819 BC080180 BC093799 BC101818 BC143543 BC143546 BC143548 CH471126 CR456967 CR542114
GenPept AAC39870 AAD27807 AAH32819 AAH80180 AAH93799 AAI01819 AAI43544 AAI43547 AAI43549 BAA25572 CAG33248 CAG46911 EAW56874

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca