Version 5.4
Homo sapiens Protein: KCNJ5
Summary
InnateDB Protein IDBP-75992.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNJ5
Protein Name potassium inwardly-rectifying channel, subfamily J, member 5
Synonyms CIR; GIRK4; KATP1; KIR3.4; LQT13;
Species Homo sapiens
Ensembl Protein ENSP00000339960
InnateDB Gene IDBG-75990 (KCNJ5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005515 protein binding
GO:0015467 G-protein activated inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003277 Potassium channel, inwardly rectifying, Kir3.4
IPR014756 Immunoglobulin E-set
IPR016449 Potassium channel, inwardly rectifying, Kir
PFAM PF01007
PRINTS PR01330
PR01320
PIRSF PIRSF005465
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48544
PhosphoSite PhosphoSite-P48544
TrEMBL H9A8L0
UniProt Splice Variant
Entrez Gene 3762
UniGene Hs.632109
RefSeq
HUGO HGNC:6266
OMIM 600734
CCDS CCDS8479
HPRD 09010
IMGT
EMBL AK312837 AP000920 BC069386 BC069482 BC069499 BC069571 BC074838 BC074839 D50134 JN859132 JN859133 L47208 U39195 U52154 X83582
GenPept AAB07045 AAB07269 AAB53093 AAH69386 AAH69482 AAH69499 AAH69571 AAH74838 AAH74839 AFB82769 AFB82770 BAA08814 BAG35691 CAA58565

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca