InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GALK1

Summary

InnateDB Protein

IDBP-760526.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GALK1

Protein Name

Synonyms

GALK; GK1; HEL-S-19;

Species

Homo sapiens

Ensembl Protein

ENSP00000465930

InnateDB Gene

IDBG-68888 (GALK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	15 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004335	galactokinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005534	galactose binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006012	galactose metabolic process
GO:0019388	galactose catabolic process
GO:0019402	galactitol metabolic process
GO:0044281	small molecule metabolic process
GO:0046835	carbohydrate phosphorylation

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000705 Galactokinase
IPR001174 Galactokinase/homoserine kinase
IPR006204 GHMP kinase N-terminal domain
IPR006206 Mevalonate/galactokinase
IPR013750 GHMP kinase, C-terminal domain
IPR019539 Galactokinase galactose-binding domain
IPR020568 Ribosomal protein S5 domain 2-type fold

PFAM

PF00288
PF08544
PF10509

PRINTS

PR00473
PR00960
PR00959

PIRSF

PIRSF000530

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt