Version 5.4
Homo sapiens Protein: YWHAE
Summary
InnateDB Protein IDBP-761970.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YWHAE
Protein Name
Synonyms 14-3-3E; HEL2; KCIP-1; MDCR; MDS;
Species Homo sapiens
Ensembl Protein ENSP00000460712
InnateDB Gene IDBG-14629 (YWHAE)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 439 experimentally validated interaction(s) in this database.
They are also associated with 142 interaction(s) predicted by orthology.
Experimentally validated
Total 439 [view]
Protein-Protein 433 [view]
Protein-DNA 5 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 142 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019904 protein domain specific binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000308 14-3-3 protein
IPR023410 14-3-3 domain
PFAM PF00244
PRINTS PR00305
PIRSF PIRSF000868
SMART SM00101
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL I3L3T1
UniProt Splice Variant
Entrez Gene 7531
UniGene Hs.704053
RefSeq
HUGO HGNC:12851
OMIM 605066
CCDS
HPRD 05457
IMGT
EMBL AC032044
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca