Version 5.4
Homo sapiens Protein: TK1
Summary
InnateDB Protein IDBP-762108.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TK1
Protein Name
Synonyms TK2;
Species Homo sapiens
Ensembl Protein ENSP00000468278
InnateDB Gene IDBG-70500 (TK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 317 experimentally validated interaction(s) in this database.
Experimentally validated
Total 317 [view]
Protein-Protein 314 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004797 thymidine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication
GO:0009157 deoxyribonucleoside monophosphate biosynthetic process
GO:0016310 phosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001267 Thymidine kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00265
PRINTS
PIRSF PIRSF035805
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL K7ERJ1
UniProt Splice Variant
Entrez Gene 7083
UniGene Hs.624417
RefSeq
HUGO HGNC:11830
OMIM 188300
CCDS
HPRD 01771
IMGT
EMBL AC021593 AC087645
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca