Version 5.4
Homo sapiens Protein: PYCR1
Summary
InnateDB Protein IDBP-762790.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PYCR1
Protein Name
Synonyms ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR;
Species Homo sapiens
Ensembl Protein ENSP00000464098
InnateDB Gene IDBG-72880 (PYCR1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 20 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004735 pyrroline-5-carboxylate reductase activity
Biological Process
GO:0006561 proline biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal
PFAM PF03807
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3QR88
UniProt Splice Variant
Entrez Gene 5831
UniGene Hs.163451
RefSeq
HUGO HGNC:9721
OMIM 179035
CCDS
HPRD 01528
IMGT
EMBL AC145207
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca