Version 5.4
Homo sapiens Protein: HGS
Summary
InnateDB Protein IDBP-762893.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HGS
Protein Name
Synonyms HRS;
Species Homo sapiens
Ensembl Protein ENSP00000458987
InnateDB Gene IDBG-72504 (HGS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 203 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 203 [view]
Protein-Protein 203 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR000306 FYVE zinc finger
IPR002014 VHS
IPR003903 Ubiquitin interacting motif
IPR008942 ENTH/VHS
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
IPR018205 VHS subgroup
PFAM PF01363
PF00790
PF02809
PRINTS
PIRSF
SMART SM00064
SM00726
SM00288
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL I3L1P5
UniProt Splice Variant
Entrez Gene 9146
UniGene Hs.728531
RefSeq
HUGO HGNC:4897
OMIM 604375
CCDS
HPRD 05085
IMGT
EMBL AC139530
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca