InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KLK7

Summary

InnateDB Protein

IDBP-763276.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KLK7

Protein Name

Synonyms

hK7; PRSS6; SCCE;

Species

Homo sapiens

Ensembl Protein

ENSP00000470538

InnateDB Gene

IDBG-65268 (KLK7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity
GO:0008236	serine-type peptidase activity

Biological Process

GO:0006508	proteolysis
GO:0008544	epidermis development
GO:0022617	extracellular matrix disassembly
GO:0030198	extracellular matrix organization

Cellular Component

GO:0005576	extracellular region
GO:0097209	epidermal lamellar body

Protein Structure and Domains

PDB ID

InterPro

IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain

PFAM

PF00089

PRINTS

PR00722

PIRSF

SMART

SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P49862

PhosphoSite

PhosphoSite-P49862

TrEMBL

X2J289

UniProt Splice Variant

Entrez Gene

5650

UniGene

Hs.151254

RefSeq

NP_005037

HUGO

HGNC:6368

OMIM

604438

CCDS

CCDS12812

HPRD

05115

IMGT

EMBL

AC011483 AF166330 AF243527 AF332583 AF411214 AF411215 AK289660 AK295313 AY601109 BC032005 CH471135 KF963189 L33404

GenPept

AAC37551 AAD49718 AAG33360 AAH32005 AAK69624 AAN03662 AAN03663 AAU04540 AHN52223 BAF82349 BAG58291 EAW71959 EAW71960 EAW71961