InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PIN1

Summary

InnateDB Protein

IDBP-763469.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PIN1

Protein Name

Synonyms

DOD; UBL5;

Species

Homo sapiens

Ensembl Protein

ENSP00000466962

InnateDB Gene

IDBG-26087 (PIN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 256 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	256 [view]
Protein-Protein	251 [view]
Protein-DNA	3 [view]
Protein-RNA	1 [view]
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005515	protein binding
GO:0016853	isomerase activity
GO:0031434	mitogen-activated protein kinase kinase binding
GO:0032794	GTPase activating protein binding
GO:0050815	phosphoserine binding
GO:0050816	phosphothreonine binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0001934	positive regulation of protein phosphorylation
GO:0006457	protein folding
GO:0007049	cell cycle
GO:0007088	regulation of mitosis
GO:0019221	cytokine-mediated signaling pathway
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032321	positive regulation of Rho GTPase activity
GO:0032465	regulation of cytokinesis
GO:0032480	negative regulation of type I interferon production
GO:0045087	innate immune response (InnateDB)
GO:0051443	positive regulation of ubiquitin-protein transferase activity
GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
GO:0070373	negative regulation of ERK1 and ERK2 cascade
GO:2000146	negative regulation of cell motility