Version 5.4
Homo sapiens Protein: PITPNC1
Summary
InnateDB Protein IDBP-763768.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PITPNC1
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000463626
InnateDB Gene IDBG-65469 (PITPNC1)
Protein Structure
UniProt Annotation
Function Phosphatidylinositol transfer proteins mediate the monomeric transport of lipids by shielding a lipid from the aqueous environment and binding the lipid in a hydrophobic cavity. Able to transfer phosphatidylinositol in vitro. {ECO:0000269PubMed:10531358}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:10531358}.
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:10531358}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0008526 phosphatidylinositol transporter activity
Biological Process
GO:0006810 transport
GO:0007165 signal transduction
GO:0015914 phospholipid transport
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001666 Phosphatidylinositol transfer protein
PFAM PF02121
PRINTS PR00391
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKF7
PhosphoSite PhosphoSite-Q9UKF7
TrEMBL J3QS95
UniProt Splice Variant
Entrez Gene 26207
UniGene Hs.631157
RefSeq NP_858057
HUGO HGNC:21045
OMIM 605134
CCDS CCDS58587
HPRD 05504
IMGT
EMBL AC079331 AC110921 AF171102 AK290838 BC007905 BC067095
GenPept AAF06148 AAH07905 AAH67095 BAF83527

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca